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HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Agrawal-Singh S, Bagri J, Giotopoulos G, Azazi DMA, Horton SJ, Lopez CK, Anand S, Bach AS, Stedham F, Antrobus R, Houghton JW, Vassiliou GS, Sasca D, Yun H, Whetton AD, Huntly BJP. Agrawal-Singh S, et al. Among authors: houghton jw. Blood. 2023 Apr 6;141(14):1737-1754. doi: 10.1182/blood.2022016528. Blood. 2023. PMID: 36577137 Free PMC article.
A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.
Ocasio CA, Baggelaar MP, Sipthorp J, Losada de la Lastra A, Tavares M, Volarić J, Soudy C, Storck EM, Houghton JW, Palma-Duran SA, MacRae JI, Tomić G, Carr L, Downward J, Eggert US, Tate EW. Ocasio CA, et al. Among authors: houghton jw. Nat Biotechnol. 2024 Jan 8. doi: 10.1038/s41587-023-02030-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38191663
Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
Nightingale K, Potts M, Hunter LM, Fielding CA, Zerbe CM, Fletcher-Etherington A, Nobre L, Wang ECY, Strang BL, Houghton JW, Antrobus R, Suarez NM, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Nightingale K, et al. Among authors: houghton jw. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2108173119. doi: 10.1073/pnas.2108173119. Proc Natl Acad Sci U S A. 2022. PMID: 35105802 Free PMC article.
13 results